Topic: LaxativesLaxatives abuses
Laxatives abuse occurs regularly in four groups of patients: (1) those with anorexia or bulimia,
(2) those who obtain secondary gain from illness (e.g., disability payments or attention from relatives),
(3) those with Munchausen syndrome, and (4) those who are dependent on others for health care and
who are poisoned by their caregivers (caregivers who do this are usually motivated by the desire
to demonstrate their devotion to the patients).
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Laxatives Precautions
Short term use of laxatives is generally safe except in appendicitis, fecal impaction, or intestinal
obstruction. Lactulose is composed of two sugar molecules; galactose and fructose, and should not
be administered to patients who require a low galactose diet.
Chronic use of laxatives may result in fluid and electrolyte imbalances, steatorrhea, osteomalacia,
diarrhea, cathartic colon, and liver disease. Excessive intake of mineral oil may cause impaired
absorption of oil soluble vitamins, particularly A and D. Excessive use of magnesium salts may cause
hypermanesemia.
Lactulose and magnesium sulfate are pregnancy category B. Casanthranol, cascara sagrada, danthron,
docusate sodium, docusate calcium, docusate potassium, mineral oil and senna are category C.
Casanthranol, cascara sagrada and danthron are excreted in breast milk, resulting in
a potential
increased incidence of diarrhea in the nursing infant.
Senokot is a chemical combination laxative, containing a stimulant laxative and stool softener. Reaction time: 6-12 hours.
Not recommended for long term usage.
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